Wednesday, November 17, 2010

LRR: Local Recurrence

Which patients appropriate?

(young age is powerful risk factor for local recurrence; important limitation
of MammoSite device is that breast tissue must be greater than 3cm in
thickness where the device is placed and there must be at least 7-to-10
mm of distance between the MammoSite balloon and skin to prevent
skin injury and possible wound breakdown.)

Because local recurrence has minimal impact on survival, could we define
a patient group with a low enough risk that no XRT (i.e., hormone
therapy only) is necessary? (recent data for women >70 shows LRR 4%
without XRT and 1% with XRT)

Will the excellent 3-5 year results for each of these partial breast treatment
techniques hold up over time?

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